Retinal Analysis

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Automated lesion detection in retinal images

Retinal Analysis Tool, an Aphelion™ stand-alone application, is an advanced and powerful tool for studying the fundus of the eye, using retinographic images. The Tool's processing of fundus images is fully automatic. Its underlying methodology was originally developed in partnership with two prestigious institutes: the Center for Mathematical Morphology at the School of Mines in Paris, and the Lariboisière Hospital in Paris, France1.

Current use of the Retinal Analysis Tool is for disease research only. However, this software is also available for integration into system applications for clinical uses, subject to approval by applicable regulatory agencies. Such applications could include diabetic retinopathy and age-related macular degeneration (ARMD).

The following tasks are performed on a color, angiographic image without human interaction:

  • Filtering to enhance the image
  • Locating the papilla (the optical nerve)
  • Analyzing the blood vessel network
  • Detecting the branching points
  • Detecting micro-aneurysms
  • Detecting exudates and hemorrhages
  • Locating the macula as the central dark area
Retina image

Detection of retinal lesions

Retina image

Graphical User Interface

In addition to its graphical user interface and image processing tools, a set of measurements is provided to quantify images:

  • Micro-aneurysm count
  • Number of vessel network branch points
  • Mean blood vessel diameter
  • Papilla size to evaluate glaucoma progression
  • Image and papilla densitometry data

Main benefits of the Retinal Analysis Tool:

  • Provides reproducible results
  • Same technique can be applied to retinal biometry applications
  • Easy-to-use application requiring no training or software expertise
  • Images and measurements are automatically saved to an internal database
  • Users can annotate images to manually mark lesions

1 The original development work was funded by the French Ministry of Research.